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Peptide record

TPDB92848

TatsMTS (TMG) (CPP71) Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB92848
TatsMTS (TMG) (CPP71)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA
Sequence
GRKKRRQRRRMVSAL
Physicochemical Analysis
C77H148N36O18S1
NDCEHIFPTWY
R
1898.31
13.10
8
0
4
+8
6.67
-1.853
52.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
6
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
1
L
2
K
1
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C77H148N36O18S1
1898.31
13.10
+8
6.67
-1.853
Conjugated with TAMRA
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Dh5Α

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
TAMRA dye and GFP expression plasmids
Cytoplasm
Penetration efficiency- 3266.25325A.U.
In vitro
CCCCCTTSCCCCSSSCCCC
Additional Detail Fields 1 fields
CCCCCTTSCCCCSSSCCCC