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Peptide record

TPDB92844

TAT Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB92844
TAT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation Chemical: UNC7938 molecule N-terminal: Conjugated with Tetramethylrhodamine (TMR)
Sequence
GRKKRRQRRRG-NH2
Physicochemical Analysis
C57H112N32O13
ANDCEHILMFPSTWYV
R
1453.72
13.10
8
0
0
+8
7.44
-3.555
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C57H112N32O13
1453.72
13.10
+8
7.44
-3.555
Amidation
UNC7938 molecule
L
Cationic
Linear
Conjugated with Tetramethylrhodamine (TMR)
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Neuro-2A And HeLa Cell Lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Protein derived
Fluorophore tetramethylrhodamine UNC7938
Endosomes, Cytosol And Nucleus
Endocytosis
In vitro