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Peptide record

TPDB92839

CADY Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB92839
CADY
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Cysteamide group N-terminal: Acetylation
Sequence
Ac-GLWRALWRLLRSLWRLLWRA
Physicochemical Analysis
C127H197N39O22
NDCEQHIKMFPTYV
L
2622.21
13.00
5
0
13
+5
-7.47
0.145
146.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
22000
838.99
1
Residue Composition
number
2
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
7
L
0
K
0
M
0
F
0
P
1
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 7 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
20
C127H197N39O22
2622.21
13.00
+5
-7.47
0.145
Cysteamide group
L
Amphipathic
Linear
Acetylation
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HDFs

Assay & Model

female Sprague-Dawley rats
female Sprague-Dawley rats

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Nucleic acid (siRNA)
In vitro and in vivo
CTHHHHHHHHHHHHHHHCCC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHHHHCCC