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Peptide record

TPDB92831

peptide 15 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB92831
peptide 15
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
GLWRALWRGLRSLWKKKRKV
Physicochemical Analysis
C120H197N39O22
NDCEQHIMFPTY
RLK
2538.13
12.89
8
0
9
+8
-0.54
-0.835
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
650.08
1
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
1
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
20
C120H197N39O22
2538.13
12.89
+8
-0.54
-0.835
Free
L
Amphipathic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
5(6)-carboxyfluorescein (FAM) dye
375.17 RFU
In vitro
CTHHHHHHHHHHHHHHHHCC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHHHHHCC