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Peptide record

TPDB92825

ppTG1 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB92825
ppTG1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA Chemical: Lys side chain amine at the C-terminus
Sequence
GLFKALLKLLKSLWKLLLKA
Physicochemical Analysis
C115H198N26O22
RNDCEQHIMPTYV
L
2297.00
11.12
5
0
13
+5
-3.27
0.950
185.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
239.44
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
9
L
5
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 9 K: 5 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C115H198N26O22
2297.00
11.12
+5
-3.27
0.950
Conjugated with TAMRA
Lys side chain amine at the C-terminus
L
Amphipathic
Linear
Free
NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

By-2 Cells Leaves Of Nicotiana Benthamiana, Arabidopsis Thaliana, Tomato (Solanum Lycopersicum), Poplar (Hybrid Aspen Populus Tremula×Tremuloides Line T89), And Rice (Oryza Sativa).

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
TAMRA dye
In vitro
CTHHHHHHHHHHHHTTTTTC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHTTTTTC