Peptide record

TPDB92818

CF-Vim-TBS.58-81 Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB92818
CF-Vim-TBS.58-81
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with 5(6)-Carboxyfluorescein
Sequence
GGAYVTRSSAVRLRSSVPGVRLLQ-NH2
Physicochemical Analysis
C109H189N37O32
NDCEHIKMFW
RSV
2529.93
12.40
4
0
10
+4
2.28
0.096
105.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
58.89
7
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
0
I
3
L
0
K
0
M
0
F
1
P
4
S
1
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 1 S: 4 T: 1 W: 0 Y: 1 V: 4
Chemical Descriptors
24
C109H189N37O32
2529.93
12.40
+4
2.28
0.096
Amidation
L
Linear
Conjugation with 5(6)-Carboxyfluorescein
NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human glioma T98G cells, U251 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (Carboxyfluorescein)
Cytoplasm and nucleus
Lipid-raft mediated endocytosis
In vitro
CCCCCCCCCCCCCSCCCTTCCSCC
Additional Detail Fields 1 fields
CCCCCCCCCCCCCSCCCTTCCSCC