Peptide record

TPDB92815

MPG-EGFP Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92815
MPG-EGFP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 24-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, Peptipedia, and PerseuCPP, with an available 3D structural model.
N-terminal: Conjugation with EGFP
Sequence
GALFLGWLGAAGSTMGAPKKKRKV
Physicochemical Analysis
C112H186N32O27S1
NDCEQHIY
G
2444.97
11.80
5
0
11
+5
0.04
0.058
77.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
224.95
2
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
0
I
3
L
4
K
1
M
1
F
1
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 3 K: 4 M: 1 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
24
C112H186N32O27S1
2444.97
11.80
+5
0.04
0.058
Free
L
Amphipathic
Linear
Conjugation with EGFP
NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

The mouse macrophage J774 A.1 cells

Assay & Model

Zebrafish
Zebrafish

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Protein (eGFP)
In vitro and in vivo
CCCSSSSSSSSCCTTCTTTTTTCC
Additional Detail Fields 1 fields
CCCSSSSSSSSCCTTCTTTTTTCC