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Peptide record

TPDB92802

Glu-Oct-6 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB92802
Glu-Oct-6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with FITC
Sequence
EEEAAGRKRKKRT
Physicochemical Analysis
C63H115N25O21
NDCQHILMFPSWYV
REK
1558.76
10.80
6
3
2
+3
11.27
-2.554
15.38
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
3
E
0
Q
1
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 3 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C63H115N25O21
1558.76
10.80
+3
11.27
-2.554
Conjugation with FITC
L
Linear
Free
N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

DU-145 and LNCaP

Source & Reference

CPPsite3.0
CPPsite3
US 20100137187

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Fluorophore (FITC)
Cytoplasm and nucleus
High relative to Oct-6
Energy dependent pathway
In vitro
CCCSSTTTTCCCC
Additional Detail Fields 1 fields
CCCSSTTTTCCCC