Back to search

Peptide record

TPDB92776

cR9 Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92776
cR9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, and Peptipedia, with an available 3D structural model.
Chemical: PLA-nanoparticles
Sequence
CRRRRRRRRR
Physicochemical Analysis
C57H115N37O11S1
ANDEQGHILKMFPSTWYV
R
1526.84
12.94
9
0
0
+9
7.05
-3.800
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
9
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C57H115N37O11S1
1526.84
12.94
+9
7.05
-3.800
Free
PLA-nanoparticles
L
Cationic
Cyclic
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Caco-2 Cells

Assay & Model

Female Wistar rats(150- 200g)
Female Wistar rats(150- 200g)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Cyclic L Cationic
Synthetic
Liraglutide (125I-radiolabeled LRT)
Nucleus
4.5 fold increase in the oral bioavailability
In vitro and in vivo