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Peptide record

TPDB92721

Pep-1 Blood-Brain Barrier Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92721
Pep-1
Blood-Brain Barrier Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
BBPpredict CPPsite3.0 TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Blood-Brain Barrier, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from BBPpredict, CPPsite3.0, and TumorHoPe2.0, with an available 3D structural model.
Chemical: FAM loaded liposomes
Sequence
CGEMGWVRC
Physicochemical Analysis
C42H65N13O12S3
ANDQHILKFPSTY
CG
1040.24
6.14
1
1
3
-0
0.36
0.156
32.22
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
540.74
2
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
1
E
0
Q
2
G
0
H
0
I
0
L
0
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
9
C42H65N13O12S3
1040.24
6.14
-0
0.36
0.156
Free
FAM loaded liposomes
L
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HUVECs And U87 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Doxorubicin (DOX)
Receptor mediated endocytosis
In vitro
CCCCCCCSSCCCC
Additional Detail Fields 1 fields
CCCCCCCSSCCCC