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Peptide record

TPDB92716

CAR Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92716
CAR
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Conjugation with micelles with green fluorescent 5-carboxyfluorescein
Sequence
CARSKNKDC
Physicochemical Analysis
C38H69N15O14S2
EQGHILMFPTWYV
CK
1024.18
9.11
3
1
1
+2
3.92
-1.478
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.20
4
Residue Composition
number
1
A
1
R
1
N
1
D
2
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C38H69N15O14S2
1024.18
9.11
+2
3.92
-1.478
Conjugation with micelles with green fluorescent 5-carboxyfluorescein
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Rat pulmonary arterial smooth muscle (PASM) cells

Assay & Model

Adult male Sprague–Dawley (SD) rats
Adult male Sprague–Dawley (SD) rats

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (5-carboxyfluorescein), Nanoparticle (fasudi loaded micelles)
In vitro and in vivo
CCSCTTCCC
Additional Detail Fields 1 fields
CCSCTTCCC