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Peptide record

TPDB92714

FHV Peptide Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB92714
FHV Peptide
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 21-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with hca (4-(7-hydroxycoumaryl)-acetyl)
Sequence
ASMWERVKSIIKSSLAAASNI-NH2
Physicochemical Analysis
C99H168N28O30S1
DCQGHFPTY
S
2262.65
10.59
3
1
11
+2
1.70
0.305
107.14
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
243.08
6
Residue Composition
number
4
A
1
R
1
N
0
D
0
C
1
E
0
Q
0
G
0
H
3
I
1
L
2
K
1
M
0
F
0
P
5
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 3 L: 1 K: 2 M: 1 F: 0 P: 0 S: 5 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
21
C99H168N28O30S1
2262.65
10.59
+2
1.70
0.305
Amidation
L
Linear
Conjugation with hca (4-(7-hydroxycoumaryl)-acetyl)
N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

NIH-3T3

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore [hca (4-(7-hydroxycoumaryl)-acetyl)]
Cytoplasm
In vitro
CCHHHHHHHHGGGTTTCCSCC
Additional Detail Fields 1 fields
CCHHHHHHHHGGGTTTCCSCC