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Peptide record

TPDB92698

F3 Cell-penetrating Peptides Tumor-homing Peptides standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB92698
F3
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP TumorHoPe2.0
standard
No
A 34-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer
Sequence
AKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
Physicochemical Analysis
C166H289N53O44
NCGHIMFTWY
K
3731.45
11.31
12
3
8
+9
19.54
-1.712
37.65
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
6
A
3
R
0
N
1
D
0
C
2
E
1
Q
0
G
0
H
0
I
1
L
9
K
0
M
0
F
8
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 3 N: 0 D: 1 C: 0 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 9 M: 0 F: 0 P: 8 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
34
C166H289N53O44
3731.45
11.31
+9
19.54
-1.712
Free
L
Linear
Conjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer
N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HL-60 and MDA-MB-435

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein)
Cytoplasm but mailny in the nucleus
Energy dependent pathway
In vitro
CCCCCCSSSCCSSCSSSSSCCCCCCTTSCCCCCC
Additional Detail Fields 1 fields
CCCCCCSSSCCSSCSSSSSCCCCCCTTSCCCCCC