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Peptide record

TPDB92697

linTT1 Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92697
linTT1
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CPPsite3.0 TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CPPsite3.0 and TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation Chemical: FAM-labeled dextran- coated and PEGylated paramagnetic iron oxide nanoworms (NW)
Sequence
AKRGARSTA-NH2
Physicochemical Analysis
C36H68N16O12
NDCEQHILMFPWYV
A
917.04
12.41
3
0
3
+3
2.38
-1.044
33.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H68N16O12
917.04
12.41
+3
2.38
-1.044
Amidation
FAM-labeled dextran- coated and PEGylated paramagnetic iron oxide nanoworms (NW)
L
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Mkn-45P And Ct-26 Cells

Assay & Model

MKN-45P tumor-bearing athymic nude mice
MKN-45P tumor-bearing athymic nude mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Proapoptotic peptide (KLA)
In vitro and in vivo
CCCGGGGGTCCCCTTSSCC
Additional Detail Fields 1 fields
CCCGGGGGTCCCCTTSSCC