Back to search

Peptide record

TPDB92644

Deltorphan Blood-Brain Barrier Neuropeptide standard
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92644
Deltorphan
Blood-Brain Barrier Neuropeptide
Delivery and barrier-penetrating peptides Neuroactive peptides
B3Pred BBPpredict Peptipedia
standard
No
A 7-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from B3Pred, BBPpredict, and Peptipedia, with an available 3D structural model.
C-terminal: Amide group is attached
Sequence
YAFDVVG
Physicochemical Analysis
C37H51N7O11
RNCEQHILKMPSTW
V
769.85
3.10
0
1
5
-1
-0.86
1.114
97.14
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
193.54
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
7
C37H51N7O11
769.85
3.10
-1
-0.86
1.114
Amide group is attached
Linear
Similarity
Tyr-(D)Ala-Phe-Asp-Val-Val-Gly-NH2
N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source
Confocal microscopy
Presence of engineered nano particles within the brain parenchyma with particular focus on hippocamp

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Opioid-derived peptides featured by specific helix-like conformation as possible ligands to engineer
CNS parenchyma
Comined
Additional Detail Fields 1 fields
Intravenous