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Peptide record

TPDB92643

Adrenomedullin Blood-Brain Barrier Neuropeptide standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB92643
Adrenomedullin
Blood-Brain Barrier Neuropeptide
Delivery and barrier-penetrating peptides Neuroactive peptides
BBPpredict Peptipedia
standard
No
A 50-aa standard natural multi-activity (Blood-Brain Barrier and Neuropeptide) peptide sequence curated from BBPpredict and Peptipedia, with an available 3D structural model.
Chemical: Cys14-Cys19
Sequence
YRQSMNQGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGY
Physicochemical Analysis
C242H382N76O76S5
EWV
Q
5732.46
10.00
9
3
13
+5
10.43
-1.154
27.40
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
4595
80.16
21
Residue Composition
number
2
A
4
R
2
N
3
D
2
C
0
E
6
Q
5
G
1
H
2
I
1
L
4
K
3
M
2
F
2
P
4
S
4
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 2 D: 3 C: 2 E: 0 Q: 6 G: 5 H: 1 I: 2 L: 1 K: 4 M: 3 F: 2 P: 2 S: 4 T: 4 W: 0 Y: 3 V: 0
Chemical Descriptors
50
C242H382N76O76S5
5732.46
10.00
+5
10.43
-1.154
Cys14-Cys19
Linear
Similarity
Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr
[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CCCNC(N)=N)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source

Source & Reference

NA
B3Pdb

Other

frog