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Peptide record

TPDB92640

Glucagon Cell-penetrating Peptides Neuropeptide standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB92640
Glucagon
Cell-penetrating Peptides Neuropeptide
Delivery and barrier-penetrating peptides Neuroactive peptides
CPPsite3.0 Peptipedia
standard
No
A 29-aa standard natural multi-activity (Cell-penetrating Peptides and Neuropeptide) peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
C-terminal: Amidation
Sequence
HSQGTFTSDYSKYLDSRRAQDFVQWLMNT-NH2
Physicochemical Analysis
C153H225N43O49S1
CEIP
S
3482.79
7.70
4
3
10
+0
2.93
-0.990
40.34
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
8480
243.48
13
Residue Composition
number
1
A
2
R
1
N
3
D
0
C
0
E
3
Q
1
G
1
H
0
I
2
L
1
K
1
M
2
F
0
P
4
S
3
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 3 C: 0 E: 0 Q: 3 G: 1 H: 1 I: 0 L: 2 K: 1 M: 1 F: 2 P: 0 S: 4 T: 3 W: 1 Y: 2 V: 1
Chemical Descriptors
29
C153H225N43O49S1
3482.79
7.70
+0
2.93
-0.990
Amidation
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
FITC labelled
Internalization efficacy approximately 5- to 10-fold lower compared to PACAP38
In vitro
CCCTTCCCCSSSCSSCCC
Additional Detail Fields 1 fields
CCCTTCCCCSSSCSSCCC