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Peptide record

TPDB92633

Calcitonin Cell-penetrating Peptides Neuropeptide standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB92633
Calcitonin
Cell-penetrating Peptides Neuropeptide
Delivery and barrier-penetrating peptides Neuroactive peptides
CPPsite3.0 Peptipedia
standard
No
A 32-aa standard natural multi-activity (Cell-penetrating Peptides and Neuropeptide) peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
C-terminal: Amidation
Sequence
CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-NH2
Physicochemical Analysis
C151H227N39O46S3
REW
T
3420.88
7.00
2
1
11
-0
0.21
0.006
51.88
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1615
47.21
13
Residue Composition
number
2
A
0
R
2
N
1
D
2
C
0
E
2
Q
4
G
1
H
1
I
2
L
1
K
1
M
3
F
2
P
1
S
5
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 1 C: 2 E: 0 Q: 2 G: 4 H: 1 I: 1 L: 2 K: 1 M: 1 F: 3 P: 2 S: 1 T: 5 W: 0 Y: 1 V: 1
Chemical Descriptors
32
C151H227N39O46S3
3420.88
7.00
-0
0.21
0.006
Amidation
L
Cationic
Linear
Free
N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
FITC labelled
Internalization efficacy approximately 5- to 10-fold lower compared to PACAP38
In vitro
CCSSSSCCHHHHHHHHHHHTTSTTTC
Additional Detail Fields 1 fields
CCSSSSCCHHHHHHHHHHHTTSTTTC