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Peptide record

TPDB92621

IVO-24 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92621
IVO-24
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: FITC or biotin
Sequence
YPHYSLPGSSTL
Physicochemical Analysis
C61H88N14O19
ARNDCEQIKMFWV
S
1321.45
7.71
1
0
4
+0
-0.60
-0.408
65.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
225.51
6
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
2
L
0
K
0
M
0
F
2
P
3
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 2 K: 0 M: 0 F: 0 P: 2 S: 3 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
12
C61H88N14O19
1321.45
7.71
+0
-0.60
-0.408
FITC or biotin
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Targeting
Oral cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-targeting peptides and uses thereof
2013
US 8394758 B2
US 8394758 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
H460 cells (a lung cancer cell line), HCT116, BT483, PC3, PaCa, SAS cells (an oral cancer cell line)
SCID mice (4-6 weeks of age
Phage display library
M13
doxorubicin
Additional Detail Fields 4 fields
doxorubicin
H460 cells (a lung cancer cell line), HCT116, BT483, PC3, PaCa, SAS cells (an oral cancer cell line)
SCID mice (4-6 weeks of age
M13