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Peptide record

TPDB92620

P1C Anticancer standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB92620
P1C
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 7-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Acetylation
Sequence
YKSIEFC
Physicochemical Analysis
C41H60N8O12S1
ARNDQGHLMPTWV
CEIKFSY
889.03
6.28
1
1
3
-0
0.52
0.043
55.71
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
167.60
3
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
1
E
0
Q
0
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
7
C41H60N8O12S1
889.03
6.28
-0
0.52
0.043
Acetylation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

~40% reduction in cell growth at 20 µM
Anticancer

Target

Pancreatic Cancer
BXPC-3
Pancreas

Assay & Model

Cell Proliferation assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
US011214593B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.