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Peptide record

TPDB92618

Peptide 3b Anticancer iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB92618
Peptide 3b
Anticancer iDPPIV
Cardiometabolic peptides Cancer-related peptides
CancerPPD 2.0 iDPPIV Peptipedia
standard
No
A 2-aa standard natural multi-activity (Anticancer and iDPPIV) peptide sequence curated from CancerPPD 2.0, iDPPIV, and Peptipedia, with an available 3D structural model.
N-terminal: 4-azidobenzoic acid
Sequence
YD
Physicochemical Analysis
C13H16N2O6
ARNCEQGHILKMFPSTWV
DY
296.28
3.10
0
1
1
-1
0.29
-2.400
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
502.90
1
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
2
C13H16N2O6
296.28
3.10
-1
0.29
-2.400
Free
L
Linear
4-azidobenzoic acid
Antiproliferative, Anticancer
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 62.3 ± 0.02 µM
Anticancer
62.3

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 5.8 ± 0.02 µM
Anticancer
5.8

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017