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Peptide record

TPDB92615

p18-4 Anticancer Tumor-homing Peptides modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB92615
p18-4
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia TumorHoPe2.0
modified_plain
Yes
A 10-aa modified multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia and TumorHoPe2.0, with an available 3D structural model.
Modified, details unspecified
Sequence
WXEAAYQRFL
Physicochemical Analysis
C57H78N14O14
NDCGHIKMPSTV
A
1183.33
6.90
1
1
6
-0
-1.41
-0.350
59.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
590.70
2
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
10
C57H78N14O14
1183.33
6.90
-0
-1.41
-0.350
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, tumor epithelial cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Engineered breast tumor targeting peptide ligand modified liposomal doxorubicin and the effect of peptide density on anticancer activity
2013
Shahin M et al. Biomaterials. 2013 May 34(16):4089-4097.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-435, MCF-7 and MCF10A
Tumor-bearing nude mice (MDA-MB-435 xenograft model)
Synthetic
DIPEA,HCTU/HOBt/ NMM
Additional Detail Fields 3 fields
DIPEA,HCTU/HOBt/ NMM
MDA-MB-435, MCF-7 and MCF10A
Tumor-bearing nude mice (MDA-MB-435 xenograft model)