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Peptide record

TPDB92611

p160 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92611
p160
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia dbACP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, dbACP, StackTHP, and other sources, with an available 3D structural model.
C-terminal: C -terminal conjugation with FITC via additional lysine
Sequence
VPWMEPAYQRFL
Physicochemical Analysis
C74H105N17O17S1
NDCGHIKST
P
1536.81
6.90
1
1
7
-0
-0.50
-0.200
65.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
6990
454.84
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
0
I
1
L
0
K
1
M
1
F
2
P
0
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 1 F: 1 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
12
C74H105N17O17S1
1536.81
6.90
-0
-0.50
-0.200
C -terminal conjugation with FITC via additional lysine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Human breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Preclinical evaluation of the breast cancer cell-binding peptide, p160
2005
Askoxylakis V et al. Clin Cancer Res. 2005 Sep 15 11(18):6705-12.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Breast cancer cell line MDA-MB-435,neuroblastoma cell line WAC 2, MCF-7
Female BALB/c nu/nu mice carrying human breast cancer MDA-MB-435 tumors
Synthetic
(131)I-labeled and the FITC-labeled
Additional Detail Fields 3 fields
(131)I-labeled and the FITC-labeled
Breast cancer cell line MDA-MB-435,neuroblastoma cell line WAC 2, MCF-7
Female BALB/c nu/nu mice carrying human breast cancer MDA-MB-435 tumors