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Peptide record

TPDB92610

K259-Lol Anticancer modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB92610
K259-Lol
Anticancer
Cancer-related peptides
CancerPPD 2.0
modified_plain
Yes
A 10-aa modified anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Lol = leucinol Chemical: U = 2-Aminoisobutyric acid N-terminal: Oct = 1-octanoyl
Sequence
UKLUKGLUKI
Physicochemical Analysis
C38H74N10O8
ARNDCEQHMFPSTWYV
K
799.07
10.84
3
0
3
+3
1.55
0.000
117.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C38H74N10O8
799.07
10.84
+3
1.55
0.000
Lol = leucinol
U = 2-Aminoisobutyric acid
L
Linear
Oct = 1-octanoyl
Antimicrobial and Antifungal
Trichogin GA
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 =10 µM
Anticancer
10 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.