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Peptide record

TPDB92608

HN1 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92608
HN1
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
N-terminal: lypophile (Fluorenylmethyloxycarbonyl, 4-para-iodo-benzyl, 4-para-iodo-benzoyl, 3-iodotyrosine )
Sequence
TSPLNIHNGQKL
Physicochemical Analysis
C57H96N18O18
ARDCEMFWYV
NL
1321.50
10.10
2
0
3
+1
2.67
-0.750
97.50
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
1
Q
1
G
1
H
1
I
2
L
1
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 2 K: 1 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C57H96N18O18
1321.50
10.10
+1
2.67
-0.750
lypophile (Fluorenylmethyloxycarbonyl, 4-para-iodo-benzyl, 4-para-iodo-benzoyl, 3-iodotyrosine )
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide-based cancer imaging agents
2022
US 11419951 B2
US 11419951 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MBA-MD-231 triple negative human breast cancer cells, Human oral squamous carcinoma cell line(Cal 27), MZ-CRC1 cells, TT cell line
Female nude mice (nu/nu)(5-7 wk old), Normal female Balb/c mice (6- to 8-week old)
Phage display library
M13 single-stranded/ random peptide library
Cy5, IR800, or NIRF dye.
Additional Detail Fields 4 fields
Cy5, IR800, or NIRF dye.
MBA-MD-231 triple negative human breast cancer cells, Human oral squamous carcinoma cell line(Cal 27), MZ-CRC1 cells, TT cell line
Female nude mice (nu/nu)(5-7 wk old), Normal female Balb/c mice (6- to 8-week old)
M13 single-stranded/ random peptide library