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Peptide record

TPDB92607

HN-1 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92607
HN-1
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein/ FITC/texas red
Sequence
TSPLNIHNGQKL-NH2
Physicochemical Analysis
C57H96N18O18
ARDCEMFWYV
NL
1321.50
10.10
2
0
3
+1
2.67
-0.750
97.50
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
1
Q
1
G
1
H
1
I
2
L
1
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 2 K: 1 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C57H96N18O18
1321.50
10.10
+1
2.67
-0.750
Amidation
L
Linear
Conjugation with fluorescein/ FITC/texas red
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MDA138Tu, MDA159Tu, MDA167Tu, MDA686Tu, MDA1986Tu, and MDA177Tu cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Fluorophore (fluoresceine/ FITC/texas red)
Cytoplasm
Receptor mediated endocytosis
In vitro
CCCCCCSSSCC
Additional Detail Fields 1 fields
CCCCCCSSSCC