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Peptide record

TPDB92605

PC5-2 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92605
PC5-2
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
TDSILRSYDWTY
Physicochemical Analysis
C69H98N16O23
ANCEQGHKMFPV
DSTY
1519.63
3.88
1
2
5
-1
-0.79
-0.808
65.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
8480
558.03
6
Residue Composition
number
0
A
1
R
0
N
2
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
2
S
2
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 2 W: 1 Y: 2 V: 0
Chemical Descriptors
12
C69H98N16O23
1519.63
3.88
-1
-0.79
-0.808
WTYY
Biotinylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Lung cancer, non-small cell lung cancer (NSCLC)

Source & Reference

TumorHoPe2.0
TumorHoPe2
A Novel Peptide Enhances Therapeutic Efficacy of Liposomal Anti-Cancer Drugs in Mice Models of Human Lung Cancer
2009
Chang DK et al. PLoS One. 2009 4(1):e4171.
US 2008/0193375A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
CL1-5, PC13, Specimens of pulmonary adenocarcinoma
SCID mice bearing CL1-5-derived tumors
Phage display library
M15 phage /random peptide library
FITC, doxorubicin or vinorelbine
Additional Detail Fields 4 fields
FITC, doxorubicin or vinorelbine
CL1-5, PC13, Specimens of pulmonary adenocarcinoma
SCID mice bearing CL1-5-derived tumors
M15 phage /random peptide library