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Peptide record

TPDB92602

IVO-8 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92602
IVO-8
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: FITC or biotin
Sequence
SNPFSKPYGLTV
Physicochemical Analysis
C61H92N14O18
ARDCEQHIMW
PS
1309.48
9.74
1
0
4
+1
0.16
-0.317
56.67
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
113.79
5
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
1
K
0
M
1
F
2
P
2
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 0 F: 1 P: 2 S: 2 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
12
C61H92N14O18
1309.48
9.74
+1
0.16
-0.317
FITC or biotin
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Targeting
Oral cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-targeting peptides and uses thereof
2013
US 8394758 B2
US 8394758 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
H460 cells (a lung cancer cell line), HCT116, BT483, PC3, PaCa, SAS cells (an oral cancer cell line)
SCID mice (4-6 weeks of age
Phage display library
M13
doxorubicin
Additional Detail Fields 4 fields
doxorubicin
H460 cells (a lung cancer cell line), HCT116, BT483, PC3, PaCa, SAS cells (an oral cancer cell line)
SCID mice (4-6 weeks of age
M13