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Peptide record

TPDB92593

Novel peptide (SP94) Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92593
Novel peptide (SP94)
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
SFSIIHTPILPL
Physicochemical Analysis
C65H104N14O16
ARNDCEQGKMWYV
I
1337.62
7.85
1
0
6
+0
-0.92
1.267
162.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
3
I
2
L
0
K
0
M
1
F
2
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 3 L: 2 K: 0 M: 0 F: 1 P: 2 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C65H104N14O16
1337.62
7.85
+0
-0.92
1.267
P-I/L-L-P
Biotinylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Hepatocellular carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Hepatocellular carcinoma cell-specific peptide ligand for targeted drug delivery
2009
Lo A et al. Mol Cancer Ther. 2008 Mar 7(3):579-89.
US 2009/0136418A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
59T human hepatocellular carcinoma lines, Changliver, human hepatocellular carcinoma lines, HA22T, human hepatocellular carcinoma lines, HA22T, human hepatocellular carcinoma lines, Hep3B, human hepatocellular carcinoma lines HepG2 human hepatocellular carcinoma lines, J5, human hepatocellular carci
SCID mice bearing human hepatocellular carcinoma xenografts
Phage display library
M15 phage/12 mer peptide library
SP94 and liposomal doxorubicin
Additional Detail Fields 4 fields
SP94 and liposomal doxorubicin
59T human hepatocellular carcinoma lines, Changliver, human hepatocellular carcinoma lines, HA22T, human hepatocellular carcinoma lines, HA22T, human hepatocellular carcinoma lines, Hep3B, human hepatocellular carcinoma lines HepG2 human hepatocellular carcinoma lines, J5, human hepatocellular carci
SCID mice bearing human hepatocellular carcinoma xenografts
M15 phage/12 mer peptide library