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Peptide record

TPDB92587

Bit1 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB92587
Bit1
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: peptidyl-tRNA hydrolase 2 (Pth2)
Sequence
RPARPAR
Physicochemical Analysis
C34H62N16O8
NDCEQGHILKMFSTWYV
R
822.97
12.70
3
0
2
+3
2.99
-1.871
28.57
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C34H62N16O8
822.97
12.70
+3
2.99
-1.871
peptidyl-tRNA hydrolase 2 (Pth2)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Breast cancers
Groucho family transcriptional coregulator Amino-terminal Enhancer of Split (AES)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Application of a proapoptotic peptide to intratumorally spreading cancer therapy
2012
Renwei Chen et al. Cancer Res. 2013 Feb 15 73(4):1352-61

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
human embryonic kidney (HEK) 293T, prostate cancer PPC1, mouse breast cancer 4T1, Human tumor cell line M21, Human breast cancer cell line MCF-10CA1a, HTB-129 (MDA-MB-435S) line
Athymic nude mice, normal Balb/C mice
Synthetic
Additional Detail Fields 2 fields
human embryonic kidney (HEK) 293T, prostate cancer PPC1, mouse breast cancer 4T1, Human tumor cell line M21, Human breast cancer cell line MCF-10CA1a, HTB-129 (MDA-MB-435S) line
Athymic nude mice, normal Balb/C mice