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Peptide record

TPDB92580

R-C16 Anticancer Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB92580
R-C16
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 CPPsite3.0
standard
No
A 23-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from CancerPPD 2.0 and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Fatty acid :C16H31O
Sequence
RGWFRAMRSIARFIARERLREHL-NH2
Physicochemical Analysis
C130H211N47O29S1
NDCQKPTYV
R
2928.46
12.53
8
2
11
+5
4.22
-0.622
80.87
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
187.81
1
Residue Composition
number
3
A
7
R
0
N
0
D
0
C
2
E
0
Q
1
G
1
H
2
I
2
L
0
K
1
M
2
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 7 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 0 M: 1 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
23
C130H211N47O29S1
2928.46
12.53
+5
4.22
-0.622
Amidation
L
Linear
Fatty acid :C16H31O
Anticancer
R-Lycosin-I
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 ~ 5 µM
Anticancer
5 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

CCK-8 assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.