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Peptide record

TPDB92577

L12 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92577
L12
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: N -terminal modification for coupling with radionucleotide
Sequence
QFPPKLTNNSML
Physicochemical Analysis
C62H100N16O18S1
ARDCEGHIWYV
NLP
1389.63
10.10
1
0
4
+1
1.10
-0.567
65.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
5
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
2
L
1
K
1
M
1
F
2
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 2 K: 1 M: 1 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C62H100N16O18S1
1389.63
10.10
+1
1.10
-0.567
N -terminal modification for coupling with radionucleotide
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Lung carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Efficient in vivo selection of a novel tumor-associated peptide from a phage display library
2011
Veleva AN et al. Molecules. 2011 Jan 21 16(1):900-14.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human blood outgrowth endothelial cells (HBOEC)
Lewis lung carcinoma (LLC) tumor-bearing mice
Phage display library
M13 phage /12mer peptide library
Cu-DOTA radionuclide
Additional Detail Fields 4 fields
Cu-DOTA radionuclide
Human blood outgrowth endothelial cells (HBOEC)
Lewis lung carcinoma (LLC) tumor-bearing mice
M13 phage /12mer peptide library