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Peptide record

TPDB92570

Modified F3 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB92570
Modified F3
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CPPsite3.0 TumorHoPe2.0
standard
No
A 32-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CPPsite3.0, and TumorHoPe2.0, with an available 3D structural model.
C-terminal: Radio idionated maleimide conjugating group
Sequence
KDEPQRRSARLSAKPAPPKPEPKPKKAPAKKC
Physicochemical Analysis
C155H268N50O42S1
NGHIMFTWYV
KP
3536.20
10.96
11
3
6
+8
18.41
-1.806
27.81
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
5
A
3
R
0
N
1
D
1
C
2
E
1
Q
0
G
0
H
0
I
1
L
8
K
0
M
0
F
8
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 3 N: 0 D: 1 C: 1 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 8 M: 0 F: 0 P: 8 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
32
C155H268N50O42S1
3536.20
10.96
+8
18.41
-1.806
Radio idionated maleimide conjugating group
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Breast tumor
Nucleolin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand.
2011
Bhojani MS et al .PloS One. 2011 6(7):e22418.
US 2005/0196343 A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-435 melanoma cell line
Nude Mice bearing MDA-MB-435
Synthetic
Radio idionated maleimide conjugating group
Additional Detail Fields 3 fields
Radio idionated maleimide conjugating group
MDA-MB-435 melanoma cell line
Nude Mice bearing MDA-MB-435