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Peptide record

TPDB92567

P3378 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB92567
P3378
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia and TumorHoPe2.0, with an available 3D structural model.
C-terminal: C -terminal modification with linker SGSGC
Sequence
HPLSKHPYWSQP
Physicochemical Analysis
C70H97N19O17
ARNDCEGIMFTV
P
1476.66
9.74
3
0
3
+1
1.75
-1.550
32.50
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
6990
473.37
4
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
2
H
0
I
1
L
1
K
0
M
0
F
3
P
2
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 2 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 2 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
12
C70H97N19O17
1476.66
9.74
+1
1.75
-1.550
C -terminal modification with linker SGSGC
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Breast carcinoma
Secreted clusterin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Molecular imaging of breast tumors using a near-infrared fluorescently labeled clusterin binding peptide.
2011
Filfil R et al. Int J Cancer.2011 Nov 28.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
4T1 cells
BALB/C mice with 4T1 tumor
Phage display library
Ph.D. /12 mer peptide library
Fluoroscent dye Dy-light -680
Additional Detail Fields 4 fields
Fluoroscent dye Dy-light -680
4T1 cells
BALB/C mice with 4T1 tumor
Ph.D. /12 mer peptide library