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Peptide record

TPDB92566

(HHPHG)4 Anticancer standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB92566
(HHPHG)4
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 20-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-HHPHGHHPHGHHPHGHHPHG-NH2
Physicochemical Analysis
C100H126N44O21
ARNDCEQILKMFSTWYV
H
2280.38
8.39
12
0
0
+1
13.36
-2.320
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
12
H
0
I
0
L
0
K
0
M
0
F
4
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 12 I: 0 L: 0 K: 0 M: 0 F: 0 P: 4 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C100H126N44O21
2280.38
8.39
+1
13.36
-2.320
Amidation
L
Linear
Acetylation
Antiangiogenesis and Antitumor
Synthetic Peptide
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50=0.245 µM
Anticancer
0.245 µM

Target

Tumor
Not Available
Not Available

Assay & Model

Tropomyosin binding assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2004

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.