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Peptide record

TPDB92562

Peptide 4b Anticancer iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB92562
Peptide 4b
Anticancer iDPPIV
Cardiometabolic peptides Cancer-related peptides
CancerPPD 2.0 iDPPIV Peptipedia
standard
No
A 2-aa standard natural multi-activity (Anticancer and iDPPIV) peptide sequence curated from CancerPPD 2.0, iDPPIV, and Peptipedia, with an available 3D structural model.
N-terminal: 4-azidobenzoic acid
Sequence
HD
Physicochemical Analysis
C10H14N4O5
ARNCEQGILKMFPSTWYV
DH
270.25
4.94
1
1
0
-1
2.19
-3.350
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C10H14N4O5
270.25
4.94
-1
2.19
-3.350
Free
L
Linear
4-azidobenzoic acid
Antiproliferative, Anticancer
Synthetic
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
IC50 = 62.2 ± 0.02 µM
Anticancer
62.2

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 63.2 ± 0.03 µM
Anticancer
63.2

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
Evidence 3 Activity

Activity

IC50
IC50 = 28.4 ± 0.02 µM
Anticancer
28.4

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017
Evidence 4 Activity

Activity

IC50
IC50 = 19.9 ± 0.02 µM
Anticancer
19.9

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017