Back to search

Peptide record

TPDB92561

Peptide 5a Anticancer iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92561
Peptide 5a
Anticancer iDPPIV
Cardiometabolic peptides Cancer-related peptides
CancerPPD 2.0 iDPPIV Peptipedia
standard
No
A 2-aa standard natural multi-activity (Anticancer and iDPPIV) peptide sequence curated from CancerPPD 2.0, iDPPIV, and Peptipedia, with an available 3D structural model.
N-terminal: 4-(methylsulfonyl)benzoic acid
Sequence
HD
Physicochemical Analysis
C10H14N4O5
ARNCEQGILKMFPSTWYV
DH
270.25
4.94
1
1
0
-1
2.19
-3.350
0.00
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C10H14N4O5
270.25
4.94
-1
2.19
-3.350
Free
L
Linear
4-(methylsulfonyl)benzoic acid
Antiproliferative, Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 12.9 ± 0.23 µM
Anticancer
12.9

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2017

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.