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Peptide record

TPDB92560

MG2d Anticancer Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB92560
MG2d
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 23-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Conjugation with Texas Red
Sequence
GIGKFLHSAKKWGKAFVGQIMNC
Physicochemical Analysis
C116H182N32O27S2
RDEPTY
GK
2521.04
10.55
5
0
10
+4
0.06
0.065
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
218.16
4
Residue Composition
number
2
A
0
R
1
N
0
D
1
C
0
E
1
Q
4
G
1
H
2
I
1
L
4
K
1
M
2
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 1 G: 4 H: 1 I: 2 L: 1 K: 4 M: 1 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C116H182N32O27S2
2521.04
10.55
+4
0.06
0.065
Conjugation with Texas Red
L
Antimicrobial
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa or TM12 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Antimicrobial
Protein derived
Fluorophore (Texas Red)
Cytosol
Higher than Tat (47-57)
Transient pore formation-translocation mechanism
In vitro
CGGGTSSSTTHHHHTGGGSSCC
Additional Detail Fields 1 fields
CGGGTSSSTTHHHHTGGGSSCC