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Peptide record

TPDB92552

MPG Anticancer Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB92552
MPG
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 27-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from CancerPPD 2.0, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Cysteamidation N-terminal: Acetylation
Sequence
Ac-GALFLGFLGAAGSTMGAWSQPKKKRKV
Physicochemical Analysis
C129H208N36O32S1
NDCEHIY
G
2807.35
11.80
5
0
12
+5
-0.38
-0.004
68.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
195.91
4
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
1
Q
5
G
0
H
0
I
3
L
4
K
1
M
2
F
1
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 5 H: 0 I: 0 L: 3 K: 4 M: 1 F: 2 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C129H208N36O32S1
2807.35
11.80
+5
-0.38
-0.004
Cysteamidation
L
Linear
Acetylation
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 15.8 µM
Anticancer
15.8 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.