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Peptide record

TPDB92546

ZXR-1 Anticancer Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB92546
ZXR-1
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 dbACP CPPsite3.0
standard
No
A 16-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from CancerPPD 2.0, dbACP, and CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC via Ahx linker
Sequence
FKIGGFIKKLWRSKLA
Physicochemical Analysis
C93H150N24O18
NDCEQHMPTYV
K
1892.36
11.80
5
0
8
+5
-1.10
0.087
103.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
290.64
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
2
L
4
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 4 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C93H150N24O18
1892.36
11.80
+5
-1.10
0.087
Free
L
Amphipathic
Linear
Conjugated with FITC via Ahx linker
N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](/C=C/CN[C@H](C)CCC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorescein isothiocyanate (FITC) dye
Translocation amounts of peptides were in the following order: ZXR–1 ≈ Z2 > Z3 > Z4
In vitro
CCSCCCCSSSSCCSCCCSCC
Additional Detail Fields 1 fields
CCSCCCCSSSSCCSCCCSCC