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Peptide record

TPDB92545

GP-1 Anticancer standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB92545
GP-1
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 6-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FKEHGY-NH2
Physicochemical Analysis
C37H49N9O10
ARNDCQILMPSTWV
EGHKFY
779.85
7.75
2
1
2
+0
1.91
-1.583
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
191.06
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
1
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
6
C37H49N9O10
779.85
7.75
+0
1.91
-1.583
Amidation
L
Linear
Free
Anticancer
Ginseng Leaf Peptide
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 86.4 ± 9.46 µM
Anticancer
86.4

Target

Colorectal Cancer
CT-26
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 104 ± 11.3 µM
Anticancer
104

Target

Colon Cancer
CaCo-2
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 3 Activity

Activity

IC50
IC50 = 111 ± 12.0 µM
Anticancer
111

Target

Colon Cancer
Colo-320
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021