Back to search

Peptide record

TPDB92543

GP-2 Anticancer standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92543
GP-2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 5-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
EGFHL-NH2
Physicochemical Analysis
C28H39N7O8
ARNDCQIKMPSTWYV
EGHLF
601.66
5.13
1
1
2
-1
1.30
-0.100
78.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
1
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C28H39N7O8
601.66
5.13
-1
1.30
-0.100
Amidation
L
Linear
Free
Anticancer
Ginseng Leaf Peptide
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 114 ± 12.1 µM
Anticancer
114

Target

Colorectal Cancer
CT-26
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 154 ± 15.8 µM
Anticancer
154

Target

Colon Cancer
CaCo-2
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 3 Activity

Activity

IC50
IC50 = 142 ± 14.9 µM
Anticancer
142

Target

Colon Cancer
Colo-320
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021