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Peptide record

TPDB92538

4R22 Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92538
4R22
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: FITC labeling
Sequence
CSNIDARAC
Physicochemical Analysis
C35H61N13O14S2
EQGHLKMFPTWYV
AC
952.07
5.95
1
1
3
-0
1.46
0.089
65.56
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
13.13
4
Residue Composition
number
2
A
1
R
1
N
1
D
2
C
0
E
0
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C35H61N13O14S2
952.07
5.95
-0
1.46
0.089
FITC labeling
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Lung (major), Colon, Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor
2011
He X et al. Mol Pharm. 2011 Apr 4 8(2):430-8.
US2010/0233161A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells, H460 Cell
BALB/ C mice with lung tumor
Synthetic
T7 phage / CX7C peptide library
Liposomal doxorubicin
Additional Detail Fields 4 fields
Liposomal doxorubicin
H460, A549 cells, H226 cells, SNU484, MDA-MB-231, HT29 cells, H460 Cell
BALB/ C mice with lung tumor
T7 phage / CX7C peptide library