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Peptide record

TPDB92523

Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB92523
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CPPsite3.0 PerseuCPP TumorHoPe2.0
standard
No
A 5-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CPPsite3.0, PerseuCPP, and other sources, with an available 3D structural model.
N-terminal: Aminooxy Acetyl Group
Sequence
CRGDK
Physicochemical Analysis
C21H39N9O8S1
ANEQHILMFPSTWYV
RDCGK
577.66
8.97
2
1
0
+1
2.80
-1.960
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
1
D
1
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C21H39N9O8S1
577.66
8.97
+1
2.80
-1.960
Aminooxy Acetyl Group
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
Neuropilin-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
A versatile theranostic nanodevice based on an orthogonal bioconjugation strategy for efficient targeted treatment and monitoring of triple negative breast cancer
2020
Cano-Cortes M V et al. Nanomedicine.2020 Feb:24:102120

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
TNBC, MDA-MB-231)
FemaleNOD scid gamma mice
Synthetic
Aminooxy Acetyl Group at N-terminus, Doxorubicin (DOX)
Additional Detail Fields 3 fields
Aminooxy Acetyl Group at N-terminus, Doxorubicin (DOX)
TNBC, MDA-MB-231)
FemaleNOD scid gamma mice