Back to search

Peptide record

TPDB92518

Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92518
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: Cyclization
Sequence
CPGPEGAGC
Physicochemical Analysis
C30H47N9O12S2
RNDQHILKMFSTWYV
G
789.88
3.29
0
1
1
-1
2.30
-0.122
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
15.83
2
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
1
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 1 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C30H47N9O12S2
789.88
3.29
-1
2.30
-0.122
Cyclization
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Blood vessel
Homing
Breast cancer
Membrane-bound proline-specific aminopeptidase P

Source & Reference

TumorHoPe2.0
TumorHoPe2
Molecular specialization of breast vasculature: a breast-homing phage-displayed peptide binds to aminopeptidase P in breast vasculature
2002
Essler M et al. Proc Natl Acad Sci U S A. 2002 Feb 19 99(4):2252-7.
WO02099379A2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Malignant lesions in transgenic breast cancer miceMMTV PyMT mice, CD mice .
Phage display library
T7 phage/ CX7C peptide library
Homes to normal breast tissue blood vessels in the breast, not to other fat-rich tissues and also malignant lesions in transgenic breast cancer mice
Additional Detail Fields 2 fields
Malignant lesions in transgenic breast cancer miceMMTV PyMT mice, CD mice .
T7 phage/ CX7C peptide library