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Peptide record

TPDB92517

Lyp-2 Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92517
Lyp-2
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
CNRRTKAGC-NH2
Physicochemical Analysis
C37H69N17O12S2
DEQHILMFPSWYV
RC
1008.18
10.12
3
0
1
+3
2.53
-1.189
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.40
4
Residue Composition
number
1
A
2
R
1
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C37H69N17O12S2
1008.18
10.12
+3
2.53
-1.189
Amidation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Lymphatic vessel
Homing
Cervical Cancer
Podoplanin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Lymphatic zip codes in premalignant lesions and tumors
2006
Zhang L et al. Cancer Res. 2006 Jun 1 66(11):5696-706.
US 2007/0219134A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-435 human breast cancer cell line
K14-HPV-16 mice
Phage display library
T7 phage/CX7C peptide library
Fluoresceine
Additional Detail Fields 4 fields
Fluoresceine
MDA-MB-435 human breast cancer cell line
K14-HPV-16 mice
T7 phage/CX7C peptide library