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Peptide record

TPDB92515

Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92515
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: fluorescein isothiocyanate (FITC)/ FPR675 near-infrared fluorescence (NIRF)
Sequence
CKGGRAKDC
Physicochemical Analysis
C35H64N14O12S2
NEQHILMFPSTWYV
CGK
937.10
9.11
3
1
1
+2
3.39
-1.089
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
13.34
2
Residue Composition
number
1
A
1
R
0
N
1
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C35H64N14O12S2
937.10
9.11
+2
3.39
-1.089
fluorescein isothiocyanate (FITC)/ FPR675 near-infrared fluorescence (NIRF)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Homing
Bladder cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Bladder tumor-targeted delivery of pro-apoptotic peptide for cancer therapy
2016
Hyun-Kyung Jung et al. J Control Release. 2016 Aug 10:235:259-267.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HT1376(human bladder tumor) cell line, BEAS-2B (normal bronchial epithelial cells), Jurkat (human T lymphocytes) cell line, HUVECs (human umbilical vein endothelial cells), JEG-3 and BeWo (human trophoblastic cells)
5-week-old BALB/c nu/nu male mice
Phage Display library
D-KLAKLAKKLAKLAK (KLA) peptide
Additional Detail Fields 3 fields
D-KLAKLAKKLAKLAK (KLA) peptide
HT1376(human bladder tumor) cell line, BEAS-2B (normal bronchial epithelial cells), Jurkat (human T lymphocytes) cell line, HUVECs (human umbilical vein endothelial cells), JEG-3 and BeWo (human trophoblastic cells)
5-week-old BALB/c nu/nu male mice