Peptide record

TPDB92514

LyP-1 Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB92514
LyP-1
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
CGQKRTRGC-NH2
Physicochemical Analysis
C37H69N17O12S2
ANDEHILMFPSWYV
RCG
1008.18
10.12
3
0
0
+3
2.87
-1.433
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.40
4
Residue Composition
number
0
A
2
R
0
N
0
D
2
C
0
E
1
Q
2
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C37H69N17O12S2
1008.18
10.12
+3
2.87
-1.433
Amidation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor lymphatics, Tumor cells
Homing
Breast cancer
p32 and gC1gR

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeting of albumin-embedded paclitaxel nanoparticles to tumors
2009
Karmali PP et al. Nanomedicine. 2009 Mar 5(1):73-82.
US 2010/0172 835 A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Mice bearing MDA-MB-435 human cancer xenografts
Synthetic
Quantum dots
Additional Detail Fields 2 fields
Quantum dots
Mice bearing MDA-MB-435 human cancer xenografts