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Peptide record

TPDB92513

LyP-1 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92513
LyP-1
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
N-terminal: cysteine/ maleimidohexanoic acid
Sequence
CGNKRTRGC
Physicochemical Analysis
C36H67N17O12S2
ADEQHILMFPSWYV
RCG
994.15
10.12
3
0
0
+3
2.71
-1.433
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.57
4
Residue Composition
number
0
A
2
R
1
N
0
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H67N17O12S2
994.15
10.12
+3
2.71
-1.433
cysteine/ maleimidohexanoic acid
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell, Tumor vessel
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment
2016
Venkata Ramana Kotamraju et al. Breast Cancer (Auckl). 2016 Jun 27 9(Suppl 2):79-87.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HeLa pLuc 705, MCF10Ca1A human breast cancer cells
Nude mice
Synthetic
FAM-Cys(oligonucleotide)
Additional Detail Fields 3 fields
FAM-Cys(oligonucleotide)
HeLa pLuc 705, MCF10Ca1A human breast cancer cells
Nude mice