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Peptide record

TPDB92512

Lyp-1 Anticancer Cell-penetrating Peptides Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB92512
Lyp-1
Anticancer Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
Peptipedia CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 PerseuCPP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer, Cell-penetrating Peptides, and Tumor-homing Peptides) peptide sequence curated from Peptipedia, CellPPD, CellPPD-MOD, and other sources, with an available 3D structural model.
N-terminal: Cysteine
Sequence
CGNKRTRGC
Physicochemical Analysis
C36H67N17O12S2
ADEQHILMFPSWYV
RCG
994.15
10.12
3
0
0
+3
2.71
-1.433
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.57
4
Residue Composition
number
0
A
2
R
1
N
0
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H67N17O12S2
994.15
10.12
+3
2.71
-1.433
Cysteine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell,
Homing
p32

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted delivery system and methods of use therefor
2022
US 11512110 B2
US 11512110 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Athymic nude mice, ApoE null mice
Phage display library
T7 phage / cyclic Cx7C and linear X7 peptide library
D(KLAKLAK)2, Nanoworms(NWs), polyethylene glycol
Additional Detail Fields 3 fields
D(KLAKLAK)2, Nanoworms(NWs), polyethylene glycol
Athymic nude mice, ApoE null mice
T7 phage / cyclic Cx7C and linear X7 peptide library